Yu, Elaine: Travel Grant - 2016-2017

College of Human Ecology
Nutritional Sciences
Project Title: 
The interplay of diabetes and tuberculosis and the impact of vitamin D supplementation
Project Abstract: 
There is growing evidence of the synergistic interaction between tuberculosis (TB) and Type 2 diabetes mellitus (T2DM). Despite the public health relevance of addressing the dual burdens of diabetes and TB, key research gaps include the clinical relevance of vitamin D supplementation in the context of TB and T2DM. The proposed ancillary study will determine the effects of daily vitamin D (600, 2000, 4000 IU) or placebo on: 1) glucose homeostasis and insulin sensitivity; and 2) body composition among adults receiving treatment for pulmonary TB (n=200; 0, 2, 6, and 12 months. Ethics committees at Cornell and in India have approved the parent randomized controlled trial protocol (ClinicalTrials.gov ID: NCT01992263).